Description

The Substrate YGA1449 is a crucial reagent designed specifically for use with CLIA (Chemiluminescent Immunoassay) analyzers. This substrate is essential for quantitative detection of alkaline phosphatase (ALP) and its markers in clinical tests. Supplied in a 100 ml vial, each bottle provides enough reagent for approximately 500 tests. When combined with ALP, the APLS substrate hydrolyzes, releasing photons in proportion to the concentration of ALP present in the sample, allowing for highly accurate measurements. This makes the Substrate YGA1449 an indispensable component for various diagnostic applications, particularly in clinical laboratories that require precise enzyme activity detection.

Market Price

The Substrate YGA1449 typically falls within the price range of $45 to $50 per 100 ml vial, which provides 500 tests. This price reflects the quality, stability, and high performance of the reagent, essential for accurate clinical diagnostics.

Frequently Asked Questions

• What is the shelf life of the Substrate YGA1449? The Substrate YGA1449 has a shelf life of 12 months when stored unopened at 2-8°C. It is important to avoid storing it at room temperature or freezing it, as this can affect its stability.

• How many tests can one bottle of Substrate YGA1449 perform? Each 100 ml bottle of Substrate YGA1449 can perform approximately 500 tests, making it an efficient choice for laboratories with high testing volumes.

• How should I store the Substrate YGA1449? The substrate should be stored at 2-8°C, out of direct sunlight. After use, return it promptly to the proper temperature to maintain its stability. Do not store it at room temperature for extended periods.

Advantages and Disadvantages

Advantages:

• High Stability: The Substrate YGA1449 is highly stable when stored under the recommended conditions, ensuring consistent performance.
• Accurate and Reliable: The substrate allows for precise enzyme activity measurements, providing dependable results for diagnostic tests.
• Easy to Use: The substrate is simple to integrate into CLIA analyzers, facilitating efficient testing and data collection.
• Large Volume for High-Volume Testing: Each vial provides enough reagent for 500 tests, making it suitable for busy laboratories.

Disadvantages:

• Storage Conditions: The substrate requires specific storage conditions (2-8°C), which may require additional attention in laboratories with limited storage capacity.
• Limited Shelf Life Once Opened: Once opened, the substrate should be used quickly to avoid degradation, which could lead to inaccurate results.

Field Use

The Substrate YGA1449 is widely used in clinical laboratories for testing enzyme activity, particularly in the detection of ALP and its markers. It is integral to a variety of immunoassays, including those used in diagnosing metabolic and bone disorders. By providing highly accurate results, it ensures that clinicians can make informed decisions regarding patient care. Whether used for routine diagnostic testing or specialized assays, this substrate is an essential reagent for reliable and reproducible clinical analysis.

Recommendations

To ensure the best performance, it is crucial to store the Substrate YGA1449 correctly and handle it according to the manufacturer’s instructions. Always store the reagent in a temperature-controlled environment and avoid any exposure to sunlight. For labs with high testing volumes, consider purchasing multiple vials at once to avoid running out of stock, and ensure that the substrate is always within its expiration date for optimal results.

Technical Specifications